Metabolism in the human brain. Brain Res 1972; 47: 469-476 Murphy WJ, Eizirik E, Johnson WE, Zhang YP, Ryder OA, O'Brien SJ. Molecular phylogenetics and the origins of placental mammals. Nature 2001; 409: 614-618 Nadeau JH. Single nucleotide polymorphisms: tackling complexity. Nature 2002; 420: 517-518 Nambu T, Sakurai T, Mizukami K, Hosoy Y, Yanagisawa M, Goto K. Distribution of orexin neurons in the adult rat brain. Brain Res 1999; 827: 243-260 Oliver SG. From DNA sequence to biological function. Nature 1996; 379: 601-603 Partridge WM. Blood-brain barrier carriermediated transport and brain metabolism of aminoacids. Neurochem Res 1998; 23: 635-644 Pascucci T, Ventura R, Puglisi-Allegra S, Cabib S. Deficits in brain serotonin in a genetic mouse model of phenylketonuria. Neuroreport 2002; 13: 2561-2564 Pey AL, Desviat LR, Gamez A, Ugarte M, Perez B. Phenylketonuria: genotype-pheonotype correlations based on expression analysis of structural and functional mutations in PAH. Hum Mutat 2003; 21: 370-378 Puglisi-Allegra S, Cabib S, Pascucci T, Ventura R, Cali F, Romano V. Dramatic brain aminergic deficit in a genetic mouse model of phenylketonuria. Neuroreport 2000; 11: 13611364 Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H. Orexins and orexin receptors: a family of hypothalamus neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 1998; 92: 573585 Scammell TE, Nishino S, Mignot E, Saper CB. Narcolepsy and low CSF orexin hypocretin ; concentration after a diencephalic stroke. Neurology 2001; 56: 1751-1753 Shefer S, Tint GS, Jean-Guillaume D, Daikhin E, Kendler A, Nguyen LE, Yudkoff M, Dyer CA. Is there a relationship between 3-hydroxy-3methylglutaryl coenzyme A reductase activity 44.
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